The recently discovered carbon polymer, Graphene oxide (GO), is one of the most attractive two dimensional polymer especially in medical and clinical applications due to its large surface area, adsorption affinity with the variety of biomolecules and its optical properties. In this study, GO biomedical derivatives [poly-ethylen-glycol functionalized (PEGylated) GO with Folic acid (GOPEGFA) and poly-ethylen-glycol functionalized GO (PEGylated) with RGD peptide (GOPEGRGD)] have been synthesized and studied spectroscopically. Notably, these derivatives exhibit the fluorescence phenomenon more intensely than pristine Graphene Oxide. Fluorescence microscopy also shows the strong and bright fluorescence in three main fluorescence regions (blue, green and red) when different excitation filters put on for the same sample. As a result, these produced networks have the potential to be used as a probe for dye free fluorescence imaging and tracking. Removing the potential toxic effects of dyes is the most important advantage of this system.
Keywords: Graphene Oxide (GO), optical property, functionalized sheets, biomedical derivatives